Here are the player ratings for the Borussia Dortmund players from the game.
Despite missing several key players through injury, Borussia Dortmund looked like the better team in the first half.
"We were able to keep them quiet in the second half and they weren't able to be clinical".
Pochettino's decision to pick Jan Vertonghen as a left wing-back against Dortmund paid off handsomely as the Belgian set up Son's opener before scoring the second goal himself.
Mauricio said: "I'm so happy but it's only the first leg and we need to finish the job".
"It was a massive victory and the players deserve all the credit".
Although Tottenham still have to survive the second leg at Signal Iduna Park on March 5, they have a golden opportunity to reach the Champions League quarter-finals for the first time since 2011.
Opinion about the wisdom of the signing was mixed, to say the least, after Pulisic's 86-minute performance in Dortmund's 3-0 loss. "When you have a team in front of you like Dortmund you need to respect them", Pochettino said.
Dortmund's United States midfielder Christian Pulisic (left) and Tottenham Hotspur's Ivorian defender Serge Aurier battle for the ball during the Uefa Champions League first leg match at Wembley Stadium on Wednesday night.
"The first half was very hard".
Lloris ensured the sides went into the break level pegging after the Frenchman did well to keep out Dan-Axel Zagadou's towering header.
He made a couple of good saves, especially in the first half.
"In that moment I think we started to feel comfortable too on the bench because we started to play really well".
Lucas Moura gave Tottenham an early spark when he latched onto Davinson Sanchez's header and smashed a volley just wide from the edge of the area.
England winger Sancho hit top gear on several occasions in a mesmerising first-half display, leaving two Tottenham midfielders for dead and linking with Pulisic, whose shot was blocked at the last minute.
And Ferdinand was full of praise for the teenager at half-time at Wembley.